Description

3-Aminoquinuclidine is a high-purity, bicyclic tertiary amine building block of significant importance in advanced organic synthesis. Its rigid quinuclidine scaffold and primary amine functionality make it a versatile intermediate for constructing complex molecules with precise stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and catalyst development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting neurological and infectious diseases.
• Ligand Synthesis: Used to prepare chiral ligands and catalysts for asymmetric synthesis, enhancing enantioselectivity in critical bond-forming reactions.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry and process chemistry optimization.

Basic Information

Product Name	3-Aminoquinuclidine
CAS No.	6238-14-8
Molecular Formula	C7H14N2
Molecular Weight	126.20 g/mol
Synonyms	3-Aminoquinuclidine; 1-Azabicyclo[2.2.2]octan-3-amine; 3-Amino-1-azabicyclo[2.2.2]octane; Quinuclidin-3-amine; 3-Quinuclidinamine; NSC 106977; 3-Aminoquinuclidine dihydrochloride (salt form)
EINECS	228-350-7

Quality Control

Our 3-Aminoquinuclidine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and physical characteristics.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.