Description

(Z)-4-[(Benzyloxy)Methyl]-2-(Bromomethyl)-1,3-Dioxolane is a high-value, functionalized dioxolane derivative characterized by its benzyl-protected alcohol and reactive bromomethyl group. This compound is a versatile and critical chemical building block for advanced organic synthesis, enabling the introduction of protected diol functionalities into complex molecular architectures. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs), nucleoside analogs, and specialty polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the multi-step synthesis of complex drug molecules, particularly those requiring protected sugar or polyol moieties.
• Nucleoside & Nucleotide Chemistry: Used in the preparation of modified nucleosides and their prodrugs, where the dioxolane ring mimics sugar structures.
• Polymer Science: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Ligand & Catalyst Synthesis: Employed in the construction of chiral ligands and organocatalysts that utilize the dioxolane framework for asymmetric induction.
• Material Science Research: Utilized in surface modification and the development of novel organic frameworks and dendrimers.
• Agrochemical Synthesis: Functions as an intermediate in the production of certain herbicides and fungicides with complex stereochemistry.

Basic Information

Product Name	(Z)-4-[(Benzyloxy)Methyl]-2-(Bromomethyl)-1,3-Dioxolane
CAS No.	6204-40-6
Molecular Formula	C12H15BrO3
Molecular Weight	287.15 g/mol
Synonyms	2-(Bromomethyl)-4-[(phenylmethoxy)methyl]-1,3-dioxolane; 4-(Benzyloxymethyl)-2-bromomethyl-1,3-dioxolane; (Z)-2-(Bromomethyl)-4-(benzyloxymethyl)-1,3-dioxolane; 1,3-Dioxolane, 2-(bromomethyl)-4-[(phenylmethoxy)methyl]-; Benzyl (Z)-2-bromomethyl-1,3-dioxolane-4-ylmethyl ether
EINECS	Contact for details

Quality Control

Our (Z)-4-[(Benzyloxy)Methyl]-2-(Bromomethyl)-1,3-Dioxolane is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.