Description

4-Benzenesulfonyl-Butyric Acid is a versatile sulfonyl-containing carboxylic acid building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a sulfonyl and a carboxylic acid functional group, makes it a valuable intermediate for constructing more complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry and custom synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a sulfonyl linker or a specific carboxylic acid side chain.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its bifunctional nature aids in creating targeted bioactive compounds.
• Organic Synthesis Reagent: Serves as a versatile precursor for coupling reactions, cyclizations, and the introduction of the benzenesulfonyl moiety into target molecules in academic and industrial R&D settings.
• Material Science Research: Investigated as a monomer or modifying agent for creating specialized polymers with unique sulfone-based properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.

Basic Information

Product Name	4-Benzenesulfonyl-Butyric Acid
CAS No.	6178-52-5
Molecular Formula	C10H12O4S
Molecular Weight	228.26 g/mol
Synonyms	4-(Phenylsulfonyl)butanoic Acid; γ-(Phenylsulfonyl)butyric Acid; 4-(Benzenesulfonyl)butanoic Acid; Butyric acid, 4-(phenylsulfonyl)-; 4-Phenylsulfonylbutyric Acid; Benzenesulfonylbutyric Acid; NSC 403697
EINECS	Contact for details

Quality Control

Our 4-Benzenesulfonyl-Butyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with key parameters such as assay (HPLC), identity (IR, NMR), and impurity profiles. Specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.