Description

1,2,3,4-Tetrahydro-1,4-Methanonaphthalen-9-One is a specialized bicyclic ketone compound that serves as a versatile and high-value synthetic intermediate. Its unique bridged-ring structure makes it a critical building block for the synthesis of complex organic molecules, particularly in advanced pharmaceutical research and fine chemical manufacturing. This compound is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those with bridged polycyclic frameworks, for central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, where its rigid structure can contribute to bioactive molecule design.
• Material Science Research: Serves as a monomer or building block for advanced polymers and specialty materials requiring specific thermal or mechanical properties.
• Organic Synthesis & Catalysis: Employed as a substrate or ligand precursor in asymmetric catalysis and methodological development for constructing stereogenic centers.
• Fragrance & Flavor Chemistry: Potential use in the synthesis of high-value aroma chemicals with unique olfactory profiles due to its ketone functionality and fused ring system.
• Academic & Industrial R&D: A valuable reagent for investigating novel chemical reactions, ring transformations, and structure-activity relationships (SAR).

Basic Information

Product Name	1,2,3,4-Tetrahydro-1,4-Methanonaphthalen-9-One
CAS No.	6165-88-4
Molecular Formula	C₁₁H₁₀O
Molecular Weight	158.20 g/mol
Synonyms	9-Oxo-1,2,3,4-tetrahydro-1,4-methanonaphthalene; 1,4-Methano-1,2,3,4-tetrahydronaphthalen-9-one; 1,4-Epoxy-1,2,3,4-tetrahydronaphthalen-9-one; 9-Keto-1,2,3,4-tetrahydro-1,4-methanonaphthalene; 1,4-Methano-1,4-dihydronaphthalen-9(1H)-one; Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydride derivative (related precursor); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-1,4-Methanonaphthalen-9-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.