Description

5-Nitroindole is a versatile and high-value heterocyclic aromatic compound, serving as a critical synthetic intermediate in advanced organic chemistry. Its nitro-substituted indole structure makes it an essential building block for the development of complex molecules with significant biological and material science applications. This compound is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging its heterocyclic framework for bioactivity.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses, including palladium-catalyzed cross-coupling reactions, to construct more elaborate indole derivatives.
• Material Science: Investigated as a monomer or dopant for creating advanced organic electronic materials and functional polymers.
• Biochemical Research: Serves as a core structure for designing enzyme inhibitors and fluorescent probes in life science research.
• Dye and Pigment Synthesis: Acts as an intermediate in the production of specialized colorants and imaging agents.

Basic Information

Product Name	5-Nitroindole
CAS No.	6146-52-7
Molecular Formula	C8H6N2O2
Molecular Weight	162.15 g/mol
Synonyms	1H-Indole, 5-nitro-; 5-Nitro-1H-indole; Indole, 5-nitro-; 5-Nitroindole; NSC 40407; 5-Nitroindol; 5-Nitro-indol; 5-Nitro-1H-indole
EINECS	228-145-9

Quality Control

Our 5-Nitroindole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation via FT-IR and NMR, and residual solvent analysis. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring stringent material standards, from research to process development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	148 - 152 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.