Description

(R)-(-)-2-Methoxypropanol CAS NO 6131-59-5 is a chiral, optically active alcohol derivative widely used as a versatile chiral building block and solvent in advanced chemical synthesis. Its value lies in its ability to impart stereochemical control in the production of pharmaceuticals and fine chemicals, where the specific (R)-enantiomer is often required for biological activity. This high-purity intermediate is essential for research and manufacturing in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material or resolving agent for producing enantiomerically pure active pharmaceutical ingredients (APIs).
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of chiral ligands for metal-catalyzed asymmetric reactions.
• Specialty Solvent for Chiral Separations: Employed in chromatographic processes for the separation of enantiomers.
• Agrochemical Intermediate: Used in the synthesis of chiral herbicides, fungicides, and plant growth regulators.
• Flavor and Fragrance Ingredient Synthesis: Serves as a chiral synthon for creating stereospecific aroma compounds.
• Material Science Research: Utilized in the development of chiral polymers and liquid crystals.

Basic Information

Product Name	(R)-(-)-2-Methoxypropanol
CAS No.	6131-59-5
Molecular Formula	C4H10O2
Molecular Weight	90.12 g/mol
Synonyms	(R)-(-)-2-Methoxy-1-methylethanol; (R)-1-Methoxy-2-propanol; (R)-(-)-Propylene glycol monomethyl ether; (R)-PGME; (R)-(-)-1-Methoxy-2-propanol; (R)-2-Methoxypropan-1-ol; (R)-Methoxyisopropanol; (2R)-2-Methoxypropan-1-ol
EINECS	Contact for details

Quality Control

Our (R)-(-)-2-Methoxypropanol is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis by GC or HPLC, to ensure it meets the high standards required for chiral synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability, though short-term storage at 15-25°C is acceptable.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.400 - 1.405
Specific Rotation ([α]20D)	-10.0° to -13.0° (c=1, H2O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.