Description

4-Hydroxyamphetamine Hydrochloride is a hydrochloride salt form of a substituted amphetamine derivative, serving as a key intermediate in advanced organic synthesis. This compound is valued for its defined chemical structure and purity, which are critical for research and development processes requiring precise molecular building blocks. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of specialized compounds for neurological and metabolic research applications.

Application

• Pharmaceutical Intermediate: A crucial building block in the research and synthesis of novel pharmaceutical agents, particularly those targeting the central nervous system.
• Reference Standard: Used as a certified reference material (CRM) or analytical standard in quality control laboratories for method development and validation.
• Metabolite Studies: Employed in pharmacological and toxicological research as a metabolite or analog in studies of amphetamine-related compounds.
• Biochemical Research: Serves as a reagent in biochemical assays and research exploring neurotransmitter pathways and receptor interactions.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of complex organic molecules in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	4-Hydroxyamphetamine Hydrochloride
CAS No.	6078-07-5
Molecular Formula	C9H14ClNO
Molecular Weight	187.66 g/mol
Synonyms	para-Hydroxyamphetamine HCl; 4-HA HCl; 1-(4-Hydroxyphenyl)-2-aminopropane hydrochloride; p-Hydroxyamphetamine hydrochloride; Norpholedrine hydrochloride; Oxamphetamine hydrochloride; 4-Hydroxy-α-methylphenethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Hydroxyamphetamine Hydrochloride is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, impurity profile, and residual solvents. We support compliance with cGMP guidelines for pharmaceutical intermediates and can accommodate custom purity specifications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.