Description

Bicyclo[2.2.2]Octane-1-Carboxylic Acid is a rigid, polycyclic organic acid characterized by its unique, highly symmetrical "cage-like" bicyclic structure. This compound is a valuable and versatile building block in advanced organic synthesis, prized for its ability to impart significant steric bulk and conformational rigidity to target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring precise molecular architecture.

Application

• Pharmaceutical Intermediate: Serves as a key scaffold in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for creating conformationally restricted analogs to improve potency and metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides and pesticides where its rigid structure can enhance binding specificity to biological targets.
• Ligand and Catalyst Development: Acts as a backbone for constructing sterically demanding ligands used in asymmetric catalysis and organometallic chemistry.
• Advanced Material Precursor: Employed in the research and development of specialty polymers, dendrimers, and molecular cages with tailored physical properties.
• Academic & Industrial Research: A fundamental reagent for methodological studies in organic chemistry, including studies on strain, reactivity, and molecular recognition.

Basic Information

Item	Detail
Product Name	Bicyclo[2.2.2]Octane-1-Carboxylic Acid
CAS No.	699-55-8
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	1-Carboxybicyclo[2.2.2]octane; Bicyclo[2.2.2]octane-1-carboxylic acid; BCOA; 1-Bicyclo[2.2.2]octanecarboxylic acid; NSC 163082; Bicyclo[2.2.2]octane-1-carboxylate; 1-Carboxy-2,2,2-bicyclooctane
EINECS	211-833-5

Quality Control

Every batch of our Bicyclo[2.2.2]Octane-1-Carboxylic Acid is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing identity, purity (typically by HPLC or titration), and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood or well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.