Description

Ethynyl Propyl Ketone is a specialized organic building block featuring a reactive ketone and terminal alkyne functional group. This unique structure makes it a valuable intermediate for synthesizing more complex molecules in fine chemical and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the life sciences and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for constructing complex heterocycles or side chains.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, where its alkyne group enables click chemistry or coupling reactions.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, resins, and advanced organic materials.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for multi-step synthesis, including Sonogashira coupling and nucleophilic addition reactions.
• Flavor & Fragrance Industry: Potential use as a precursor for synthesizing specific ketone-based aroma compounds.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands for metal catalysis or as a substrate for catalytic reaction studies.

Basic Information

Product Name	Ethynyl Propyl Ketone
CAS No.	689-00-9
Molecular Formula	C6H8O
Molecular Weight	96.13 g/mol
Synonyms	1-Pentyn-3-one; 3-Pentyn-2-one; Propyl ethynyl ketone; Ethynyl propyl ketone; 2-Pentyn-4-one; 3-Oxo-1-pentyne; Acetylene propyl ketone
EINECS	211-700-8

Quality Control

Our Ethynyl Propyl Ketone is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (IR, NMR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at controlled room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. Containers should be kept tightly sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.420 - 1.430
Density (g/mL at 20°C)	0.88 - 0.92

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.