Description

4-Fluoro Benzylamine Hydrochloride is a high-purity organic salt derivative of benzylamine, featuring a fluorine substituent at the para position. This compound serves as a versatile and critical building block in advanced organic synthesis, valued for its role in introducing the 4-fluorobenzyl moiety into target molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating molecules with potential CNS, anti-inflammatory, or antimicrobial activity.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the fluorinated benzyl group can enhance biological activity and stability.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal catalysis and as a precursor for chiral auxiliaries in asymmetric synthesis.
• Peptide Modification: Acts as a reagent for introducing fluorinated aromatic groups into peptides and peptidomimetics to alter their physicochemical and binding properties.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and advanced organic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorinated probes and tags for imaging, diagnostics, and biochemical assays.

Basic Information

Product Name	4-Fluoro Benzylamine Hydrochloride
CAS No.	659-41-6
Molecular Formula	C7H9FN • HCl
Molecular Weight	161.61 (Free base) / 198.06 (Hydrochloride)
Synonyms	(4-Fluorophenyl)methanamine hydrochloride; 1-(4-Fluorophenyl)methanamine hydrochloride; 4-Fluorobenzylamine HCl; p-Fluorobenzylamine hydrochloride; 4-Fluorobenzylammonium chloride; Benzenemethanamine, 4-fluoro-, hydrochloride; α-Amino-4-fluorotoluene hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Fluoro Benzylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤1.0%
Heavy Metals	<20 ppm
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.