Description

4-Iodo-2-Nitro-1-(Trifluoromethoxy)Benzene is a high-purity, multi-functional halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring iodine, nitro, and trifluoromethoxy substituents, makes it a versatile precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing complex aromatic cores via Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethoxy and nitro groups can contribute to biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Acts as a building block for advanced electronic materials, where its halogenated and electron-withdrawing groups help fine-tune molecular polarity and luminescent properties.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis or as a scaffold for metal-organic frameworks (MOFs).
• Dye & Pigment Synthesis: Functions as an intermediate in the production of specialized dyes and pigments, leveraging its nitro and iodine substituents for color and stability modification.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry, exploring new halogenation or functionalization pathways.

Basic Information

Product Name	4-Iodo-2-Nitro-1-(Trifluoromethoxy)Benzene
CAS No.	655-71-0
Molecular Formula	C7H3F3INO3
Molecular Weight	332.99 g/mol
Synonyms	1-Iodo-4-nitro-2-(trifluoromethoxy)benzene; 2-Nitro-4-iodo-1-(trifluoromethoxy)benzene; 4-Iodo-2-nitro-α,α,α-trifluoroanisole; 1-Trifluoromethoxy-4-iodo-2-nitrobenzene; Benzene, 1-iodo-4-nitro-2-(trifluoromethoxy)-; 655-71-0; 4-Iodo-2-nitro-1-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-Nitro-1-(Trifluoromethoxy)Benzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers. Recommended storage temperature is between 15°C and 25°C. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Related Substances (HPLC)	Total impurities < 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.