Description

D-Mannoheptulose is a naturally occurring seven-carbon sugar (heptose) that functions as a specific, competitive inhibitor of hexokinase, the first enzyme in the glycolytic pathway. This unique biochemical property makes it a critical research tool for studying glucose metabolism, insulin secretion, and cellular energy regulation. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical development, and nutritional biochemistry sectors.

Application

• Biochemical Research: A key tool for investigating carbohydrate metabolism, glycolysis inhibition, and pancreatic β-cell function.
• Diabetes & Metabolic Disease Studies: Used to model and study mechanisms of insulin secretion and glucose homeostasis.
• Pharmaceutical Development: Serves as a reference standard and potential lead compound in metabolic disorder drug discovery.
• Plant Physiology Research: Studied for its role in plant carbohydrate metabolism and as a metabolite in certain plant species like avocados.
• Nutritional Science: Investigated for its effects on appetite regulation and potential metabolic impacts.
• Enzyme Kinetics: Employed as a specific substrate/inhibitor in enzymatic assays for hexokinase and related enzymes.

Basic Information

Product Name	D-Mannoheptulose
CAS No.	654-29-5
Molecular Formula	C7H14O7
Molecular Weight	210.18 g/mol
Synonyms	D-Manno-heptulose; Mannoheptulose; D-Manno-2-heptulose; 654-29-5; Avocado sugar; NSC 17784; (3S,4R,5R,6R)-1,3,4,5,6,7-Hexahydroxyheptan-2-one
EINECS	211-500-8

Quality Control

Our D-Mannoheptulose is produced and tested under strict quality management systems to ensure high purity and batch-to-batch consistency for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and specific tests. We can supply material suitable for analytical and biochemical applications, with specifications tailored to customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	[α]20/D: +29° to +31° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.