Description

2,3,5,6-Tetrafluorophenylhydrazine is a specialized fluorinated aromatic hydrazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique perfluorinated phenyl ring, which imparts enhanced stability, lipophilicity, and electronic properties to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, including potential antiviral, anticancer, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used to create novel fluorinated pesticides, herbicides, and fungicides, where the fluorine atoms can improve metabolic stability and bioavailability.
• Material Science: Building block for synthesizing fluorinated polymers, liquid crystals, and electronic materials that require specific dielectric properties and chemical resistance.
• Chemical Research: Valuable reagent for constructing heterocycles (e.g., pyrazoles, indazoles) and for use in coupling reactions and click chemistry applications.
• Dye & Pigment Industry: Intermediate for producing specialized fluorinated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	2,3,5,6-Tetrafluorophenylhydrazine
CAS No.	653-11-2
Molecular Formula	C6H4F4N2
Molecular Weight	180.10 g/mol
Synonyms	2,3,5,6-Tetrafluorophenylhydrazine; (2,3,5,6-Tetrafluorophenyl)hydrazine; Hydrazine, (2,3,5,6-tetrafluorophenyl)-; 2,3,5,6-Tetrafluoro-phenylhydrazine; Tetrafluorophenylhydrazine; 653-11-2; Perfluorophenylhydrazine (ambiguous, but commonly searched)
EINECS	211-477-1

Quality Control

We maintain stringent quality control protocols for 2,3,5,6-Tetrafluorophenylhydrazine to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity limits is provided with each shipment. We can support development projects requiring specific analytical methods or compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.