Description

3-Hydroxy-4-Methoxybenzoic Acid is a versatile aromatic carboxylic acid derivative, also known as isovanillic acid, valued for its role as a key synthetic intermediate and building block in advanced organic synthesis. Its phenolic and carboxylic acid functionalities make it a crucial precursor for the production of pharmaceuticals, agrochemicals, and specialty fine chemicals. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and agrochemical formulators seeking a reliable, high-purity intermediate.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and cardiovascular diseases.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators due to its bioactive phenolic structure.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, UV stabilizers, and polymer additives.
• Flavor and Fragrance Industry: Employed in the synthesis of complex aroma chemicals and flavoring agents.
• Biochemical Research: Used as a standard or reagent in metabolic studies and enzymatic research.
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and resins.

Basic Information

Product Name	3-Hydroxy-4-Methoxybenzoic Acid
CAS No.	645-08-9
Molecular Formula	C8H8O4
Molecular Weight	168.15 g/mol
Synonyms	Isovanillic Acid; 4-Methoxy-3-hydroxybenzoic Acid; 3-Hydroxy-p-anisic Acid; 3-Hydroxy-4-methoxybenzenecarboxylic Acid; 5-Carboxyguaiacol; NSC 403697
EINECS	211-441-1

Quality Control

Our 3-Hydroxy-4-Methoxybenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	250 - 255 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.