Description

2-Fluoro-6-Methoxynitrobenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both electron-withdrawing and electron-donating substituents, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by R&D chemists and process development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a fluorinated aromatic core for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atom can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as fluorinated polymers or small molecules for OLEDs and semiconductors.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing specialized fluorinated dyes and pigments with unique colorfastness and optical properties.
• Custom Synthesis and Contract Manufacturing: A valuable substrate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Fluoro-6-Methoxynitrobenzene
CAS No.	641-49-6
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	1-Fluoro-2-methoxy-3-nitrobenzene; 2-Fluoro-6-nitroanisole; 3-Nitro-2-fluoroanisole; 2-Methoxy-6-fluoronitrobenzene; 6-Fluoro-2-nitroanisole; Benzene, 1-fluoro-2-methoxy-3-nitro-; (2-Fluoro-6-methoxyphenyl)nitro compound
EINECS	211-389-1

Quality Control

Every batch of 2-Fluoro-6-Methoxynitrobenzene is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.