Description

5-Chloroquinoline is a versatile halogenated quinoline derivative that serves as a crucial synthetic intermediate in advanced organic chemistry. This compound matters for its role as a key building block in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and academic research laboratories focused on heterocyclic chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various quinoline-based drug candidates, including potential antimalarial and anticancer agents.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the chloroquinoline moiety contributes to biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations to create complex heterocyclic systems.
• Material Science Research: Serves as a starting material for developing organic ligands in catalysis and for creating novel organic electronic materials.
• Dye and Pigment Industry: Acts as an intermediate in the production of specialized quinoline-based dyes and colorants.

Basic Information

Product Name	5-Chloroquinoline
CAS No.	635-27-8
Molecular Formula	C9H6ClN
Molecular Weight	163.60 g/mol
Synonyms	Quinoline, 5-chloro-; 5-Chloro-quinoline; 5-Chlorochinolin; NSC 404087; 5-CQ
EINECS	211-242-6

Quality Control

Our 5-Chloroquinoline is produced under a rigorous quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	44 - 48 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.