Description

1-Chloro-3-(Tolene-p-Sulphonyloxy) Propane is a versatile organic sulfonate ester intermediate with a reactive chloropropyl group. This compound is valued for its bifunctional reactivity, enabling its use as a key building block in the synthesis of more complex molecules. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing molecular scaffolds and introducing functional groups.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing linker molecules for prodrugs or targeted therapies.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Acts as a cross-linking agent or a functional monomer to introduce sulfonate ester groups into polymer chains.
• Organic Synthesis Building Block: Employed in nucleophilic substitution reactions to alkylate amines, alcohols, or carboxylic acids, facilitating the introduction of the propane sulfonate moiety.
• Liquid Crystal & Material Science: Utilized in the research and development of advanced materials, including liquid crystal compounds and ionic liquids.
• Bioconjugation Chemistry: Can be used to modify biomolecules, such as proteins or peptides, for research and diagnostic applications.

Basic Information

Product Name	1-Chloro-3-(Tolene-p-Sulphonyloxy) Propane
CAS No.	632-02-0
Molecular Formula	C10H13ClO3S
Molecular Weight	248.72 g/mol
Synonyms	1-Chloro-3-(p-toluenesulfonyloxy)propane; 3-Chloropropyl p-toluenesulfonate; p-Toluenesulfonic acid 3-chloropropyl ester; Tosyloxypropyl chloride; 3-(p-Tolylsulfonyloxy)propyl chloride; 3-Chloro-1-propanol p-toluenesulfonate; NSC 403107
EINECS	211-173-3

Quality Control

Our 1-Chloro-3-(Tolene-p-Sulphonyloxy) Propane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets high-grade specifications suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.