Description

Ethyl Diazoacetate is a versatile and highly reactive organic compound primarily used as a key building block in organic synthesis. Its value lies in its ability to serve as a source of carbenes or as a 1,3-dipole, enabling the construction of complex molecular frameworks through cyclopropanation, cycloaddition, and homologation reactions. This makes it an indispensable reagent for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to synthesize active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of β-lactam antibiotics, heterocyclic compounds, and other complex active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of pesticides, herbicides, and plant growth regulators requiring specific cyclopropane or heterocyclic structures.
• Organic Synthesis Reagent: Employed in classic name reactions such as the Doyle-Kirmse reaction, cyclopropanation of alkenes, and [3+2] cycloadditions for constructing five-membered rings.
• Polymer & Material Science: Acts as a monomer or modifying agent for creating specialized polymers with unique properties.
• Chemical Research & Development: A fundamental tool in academic and industrial R&D labs for methodology development and exploring new synthetic pathways.
• Fine Chemical Production: Utilized in the manufacture of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Ethyl Diazoacetate
CAS No.	623-73-4
Molecular Formula	C4H6N2O2
Molecular Weight	114.10 g/mol
Synonyms	Diazoacetic Acid Ethyl Ester; Ethyl 2-Diazoacetate; Ethyl Diazoethanoate; EDA; NSC 13785; Diazoessigsaeure-aethylester (German); Acetic acid, 2-diazo-, ethyl ester
EINECS	210-806-4

Quality Control

Our Ethyl Diazoacetate is produced and handled under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, assay, and impurity profiles. We adhere to relevant ISO standards and can support regulatory documentation for research and commercial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maintain stability and extend shelf life. Keep away from heat, sparks, open flames, and strong oxidizing agents. Due to its light-sensitive nature, containers should be amber-colored or stored in opaque secondary packaging.

Specification

Item	Specification
Appearance	Yellow to orange liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.