Description

4-Chloroanisole is a versatile halogenated aromatic ether, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its ability to introduce both methoxy and chloro functional groups, enabling the construction of complex molecules for high-value applications. This compound is essential for manufacturers and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-purity building blocks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted anisole core structure.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its chloroanisole moiety is integral to biological activity.
• Liquid Crystal & Electronic Chemicals: Serves as a precursor in the manufacture of liquid crystal displays (LCDs) and other electronic materials due to its stable aromatic structure.
• Dye & Pigment Manufacturing: Acts as an intermediate for synthesizing various organic dyes and pigments, contributing to color fastness and stability.
• Fragrance & Flavor Chemistry: Utilized in the controlled synthesis of aroma chemicals, where specific halogenated anisoles are valued for their unique olfactory properties.
• Organic Synthesis & Research: A valuable reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution in academic and industrial R&D laboratories.

Basic Information

Product Name	4-Chloroanisole
CAS No.	623-12-1
Molecular Formula	C7H7ClO
Molecular Weight	142.58 g/mol
Synonyms	1-Chloro-4-methoxybenzene; p-Chloroanisole; 4-Methoxychlorobenzene; Anisole, 4-chloro-; p-Methoxychlorobenzene; 4-Chloromethoxybenzene; 4-Chlorophenyl methyl ether; NSC 406908
EINECS	210-775-5

Quality Control

Our 4-Chloroanisole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.16 - 1.18 g/cm³
Refractive Index (n20D)	1.540 - 1.545

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.