Description

4-Chlorophenetole is a versatile chlorinated aromatic ether, a key intermediate in fine chemical synthesis. Its value lies in its reactive chlorine and ether functional groups, enabling precise chemical modifications for advanced applications. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a critical building block for more complex molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a phenetole backbone.
• Agrochemical Synthesis: Used in the manufacture of herbicides, pesticides, and plant growth regulators, leveraging its aromatic chlorinated structure.
• Liquid Crystal & Dye Manufacturing: Serves as a starting material for producing advanced organic materials, including liquid crystal displays (LCDs) and specialized dyes.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic aromatic substitution to create complex organic architectures.
• Perfumery & Fragrance Intermediate: Used in the controlled synthesis of specific aromatic compounds for fragrance applications.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and material properties.

Basic Information

Product Name	4-Chlorophenetole
CAS No.	622-61-7
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	1-Chloro-4-ethoxybenzene; p-Chlorophenetole; 4-Chloro-1-ethoxybenzene; 4-Ethoxychlorobenzene; Phenetole, 4-chloro-; NSC 406850; Benzene, 1-chloro-4-ethoxy-
EINECS	210-748-7

Quality Control

Our 4-Chlorophenetole is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring reliable and traceable raw materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and oxidizing agents. Recommended storage temperature is between 15°C and 25°C (59°F and 77°F). Keep container tightly sealed when not in use to maintain quality.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	≤ 2.0% total
Density (20°C)	1.14 - 1.16 g/cm³
Refractive Index (20°C)	1.525 - 1.535

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.