Description

Tripropyl Orthoformate is an organic ester compound, specifically the tripropyl ester of orthoformic acid. This chemical serves as a versatile alkylating agent and protecting group reagent in sophisticated organic synthesis. It is primarily utilized by manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the production of active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of various active pharmaceutical ingredients (APIs), particularly as a protecting group for aldehydes and ketones.
• Agrochemical Synthesis: Used in the manufacturing of pesticides, herbicides, and fungicides as a building block for complex molecules.
• Fine Chemical Production: Employed in the synthesis of dyes, flavors, fragrances, and other specialty organic compounds.
• Cross-Coupling Reactions: Acts as an alkoxy source in metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Polymer Chemistry: Utilized as a modifier or chain transfer agent in the production of certain specialty polymers and resins.
• Laboratory Reagent: Serves as a valuable reagent in research and development laboratories for method development and scale-up studies.

Basic Information

Product Name	Tripropyl Orthoformate
CAS No.	621-76-1
Molecular Formula	C10H22O3
Molecular Weight	190.28 g/mol
Synonyms	Orthoformic Acid Tripropyl Ester; Propyl Orthoformate; Tripropoxy Methane; 1,1,1-Tripropoxymethane; HC(OCH2CH2CH3)3; Tri-n-propyl Orthoformate; Formic Acid Tripropyl Ester
EINECS	210-702-8

Quality Control

Our Tripropyl Orthoformate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments upon request, providing full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %
Refractive Index (n20D)	1.400 - 1.410
Density (20°C)	0.920 - 0.940 g/mL
Boiling Point	~ 210 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.