Description

3-Acetamidophenol is a key organic intermediate and building block in fine chemical synthesis. This compound matters for its role as a versatile precursor in the production of pharmaceuticals and other high-value specialty chemicals. Industries that require it include pharmaceutical manufacturers, research and development laboratories, and fine chemical producers focused on creating analgesic and antipyretic drug substances. Its reliable synthesis and consistent purity are critical for downstream product quality and regulatory compliance.

Application

• Pharmaceutical Intermediate: Primarily used in the synthesis of paracetamol (acetaminophen) and related analgesic compounds.
• Fine Chemical Synthesis: Serves as a versatile building block for creating more complex molecules in medicinal chemistry.
• Research & Development: Employed in academic and industrial R&D for studying metabolic pathways and developing new active pharmaceutical ingredients (APIs).
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for quality control and method validation.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of certain azo dyes and other colorants.

Basic Information

Product Name	3-Acetamidophenol
CAS No.	621-42-1
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	N-(3-Hydroxyphenyl)acetamide; 3'-Hydroxyacetanilide; m-Acetamidophenol; Metacetamol; 3-Acetaminophenol; APAP Impurity C (Paracetamol Impurity C); N-Acetyl-m-aminophenol
EINECS	210-699-0

Quality Control

Our 3-Acetamidophenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets exacting standards for use as a pharmaceutical intermediate. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.5%
Melting Point	168°C - 172°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.