Description

2-Bromo-4'-Methylacetophenone is a versatile brominated aromatic ketone that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in its reactive bromine and carbonyl groups, enabling precise functionalization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for molecules requiring a substituted acetophenone core.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoresponsive polymers.
• Fine Chemical Production: Intermediate for synthesizing dyes, fragrances, and other high-value specialty chemicals.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and nucleophilic substitution reactions.

Basic Information

Product Name	2-Bromo-4'-Methylacetophenone
CAS No.	619-41-0
Molecular Formula	C9H9BrO
Molecular Weight	213.07 g/mol
Synonyms	1-(4-Methylphenyl)-2-bromoethanone; 2-Bromo-1-(4-methylphenyl)ethanone; 4'-Methyl-2-bromoacetophenone; 2-Bromo-4'-methylacetophenone; p-Methylphenacyl bromide; 4-Methylphenacyl bromide; α-Bromo-4-methylacetophenone; 2-Bromo-1-(p-tolyl)ethanone
EINECS	210-598-7

Quality Control

Our 2-Bromo-4'-Methylacetophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	48 - 52 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.