Description

2'-Bromo-4'-Methylacetanilide is a halogenated aromatic amide compound that serves as a versatile and critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a reactive bromine substituent and a protected aniline functionality, enabling precise molecular construction for complex target molecules. This high-purity intermediate is essential for research and development chemists and process engineers in the pharmaceutical and agrochemical sectors, where it is used to build active pharmaceutical ingredients (APIs) and specialized crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those requiring bromo-substituted aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the bromomethylaniline moiety is incorporated.
• Dye and Pigment Manufacturing: Serves as a precursor for specialized azo dyes and high-performance pigments.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoresist materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions like Suzuki, Heck, and Buchwald-Hartwig amination for C-C and C-N bond formation.
• Academic & Contract Research: A valuable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	2'-Bromo-4'-Methylacetanilide
CAS No.	614-83-5
Molecular Formula	C9H10BrNO
Molecular Weight	228.09 g/mol
Synonyms	N-(2-Bromo-4-methylphenyl)acetamide; 2-Bromo-4-methylacetanilide; 1-(2-Bromo-4-methylphenyl)ethanone; Acetamide, N-(2-bromo-4-methylphenyl)-; 2-Bromo-4-methylaniline, N-acetyl derivative; 2'-Bromo-p-acetotoluidide; 4'-Methyl-2'-bromoacetanilide
EINECS	210-395-5

Quality Control

Our 2'-Bromo-4'-Methylacetanilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the high standards required for synthetic applications. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment aligns with cGMP principles where applicable, supporting our customers' regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound should be handled in accordance with good laboratory practices to prevent contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.