Description

2-Chloroquinoline is a versatile halogenated heterocyclic compound that serves as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its reactivity as a building block for constructing more complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on active pharmaceutical ingredients (APIs), specialty chemicals, and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various quinoline-based drug candidates, including antimalarial, antibacterial, and anticancer agents.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides that leverage the quinoline scaffold for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as light-emitting diodes (OLEDs) and conductive polymers.
• Dye and Pigment Manufacturing: Acts as a foundational component for synthesizing certain quinoline-derived dyes and colorants.
• Academic and R&D Laboratories: A standard reagent for methodological studies in organic synthesis, including cross-coupling and nucleophilic substitution reactions.

Basic Information

Product Name	2-Chloroquinoline
CAS No.	612-62-4
Molecular Formula	C9H6ClN
Molecular Weight	163.60 g/mol
Synonyms	Quinoline, 2-chloro-; 2-Chloro-quinoline; β-Chloroquinoline; NSC 66411; 2-Chlorochinolin; 2-Cl-Quinoline
EINECS	210-300-8

Quality Control

Our 2-Chloroquinoline is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including GC, HPLC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	44 - 48 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.