Description

1,1'-Bi-2-Naphthol (CAS NO 602-09-5) is a high-purity chiral binaphthyl compound that serves as a fundamental building block and ligand in asymmetric synthesis. Its axial chirality and rigid structure make it invaluable for creating highly selective catalytic systems, directly impacting the efficiency and yield of advanced chemical manufacturing. This product is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise stereochemical control is a critical requirement.

Application

• As a chiral ligand in asymmetric catalysis for the synthesis of active pharmaceutical ingredients (APIs).
• Key intermediate in the preparation of BINAP and other privileged chiral phosphine ligands.
• Building block for chiral polymers and materials with advanced optical properties.
• Use in chiral stationary phases for the analytical and preparative separation of enantiomers.
• Precursor for novel molecular receptors and sensors in diagnostic applications.
• Catalyst component in enantioselective carbon-carbon and carbon-heteroatom bond-forming reactions.

Basic Information

Product Name	1,1'-Bi-2-Naphthol
CAS No.	602-09-5
Molecular Formula	C₂₀H₁₄O₂
Molecular Weight	286.32 g/mol
Synonyms	BINOL; (±)-1,1'-Bi-2-naphthol; 1,1'-Binaphthalene-2,2'-diol; 2,2'-Dihydroxy-1,1'-binaphthyl; rac-BINOL; (±)-BINOL; NSC 406902; 1,1'-Binaphthyl-2,2'-diol
EINECS	210-001-9

Quality Control

Our 1,1'-Bi-2-Naphthol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity determination. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with our stringent specifications. We support cGMP and ISO standards for pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (for enantiopure grades)
Melting Point	205 - 210 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.