Description

1,2-Benzenediol, 4-[2-(Dimethylamino)-1-Hydroxyethyl]-, Hydrochloride (1:1) is a high-purity organic compound, commonly known as epinephrine hydrochloride, which serves as a critical pharmaceutical intermediate and active ingredient. Its primary value lies in its potent adrenergic activity, making it essential for the formulation of emergency medications and specialized therapeutic agents. This product is vital for manufacturers in the pharmaceutical, research, and fine chemical sectors who require a reliable and high-quality source for producing cardiovascular drugs, anaphylaxis treatments, and ophthalmic solutions.

Application

• Pharmaceutical Active Ingredient (API): Core component in the synthesis of epinephrine (adrenaline) for injection, used in cardiac arrest, anaphylaxis, and severe asthma.
• Ophthalmic Solutions: Used in the production of eye drops for treating open-angle glaucoma.
• Veterinary Medicine: Employed in emergency kits and treatments for animals.
• Biochemical Research: Serves as a standard and reagent in studies of adrenergic receptors and sympathetic nervous system pathways.
• Reference Standard: Used in analytical laboratories for quality control and method validation in pharmaceutical testing.
• Fine Chemical Synthesis: Intermediate for further chemical modifications to create novel adrenergic compounds.

Basic Information

Product Name	1,2-Benzenediol, 4-[2-(Dimethylamino)-1-Hydroxyethyl]-, Hydrochloride (1:1)
CAS No.	62-22-6
Molecular Formula	C9H14ClNO3
Molecular Weight	219.66 g/mol
Synonyms	Epinephrine Hydrochloride; Adrenaline Hydrochloride; L-Epinephrine Hydrochloride; (-)-Epinephrine Hydrochloride; 4-[1-Hydroxy-2-(methylamino)ethyl]benzene-1,2-diol hydrochloride; (R)-(-)-Adrenaline hydrochloride; Suprarenin hydrochloride; 1,2-Benzenediol, 4-[1-hydroxy-2-(methylamino)ethyl]-, hydrochloride, (R)-
EINECS	200-526-0

Quality Control

Our Epinephrine Hydrochloride is manufactured under strict quality systems to ensure it meets the rigorous standards required for pharmaceutical applications. Each batch is tested against comprehensive specifications, including identity, purity, and impurity profiles, with methods aligned to USP, EP, and BP monographs. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Specific Rotation	-50.0° to -53.5° (c = 2 in water)
pH (5% solution)	4.0 - 5.5
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.