Description

Ethanone, 1-[(2R,5R)-2-Ethoxy-5-Ethyl-2,5-Dihydro-2-Oxido-1,2-Oxaphosphol-3-Yl]-, Rel- (9Ci) is a specialized chiral organophosphorus compound of significant interest in advanced synthetic chemistry. This compound matters as a high-value chemical intermediate or ligand precursor for the development of novel catalysts and active pharmaceutical ingredients (APIs). It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for asymmetric synthesis and process development.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly those requiring specific stereochemistry.
• Catalyst Ligand Precursor: Used in the development and synthesis of chiral phosphine or phosphinite ligands for asymmetric catalysis.
• Agrochemical Research: Employed in the creation of new, more effective chiral pesticides and herbicides.
• Fine Chemical Synthesis: Acts as a versatile intermediate for producing complex, high-value specialty chemicals.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic synthesis and catalysis research.
• Material Science: Potential use in the synthesis of functionalized polymers or advanced materials with specific optical properties.

Basic Information

Product Name	Ethanone, 1-[(2R,5R)-2-Ethoxy-5-Ethyl-2,5-Dihydro-2-Oxido-1,2-Oxaphosphol-3-Yl]-, Rel- (9Ci)
CAS No.	599179-54-1
Molecular Formula	C8H15O4P
Molecular Weight	206.18 g/mol
Synonyms	1-[(2R,5R)-2-Ethoxy-5-ethyl-2,5-dihydro-2-oxido-1,2-oxaphosphol-3-yl]ethanone; (2R,5R)-3-Acetyl-2-ethoxy-5-ethyl-1,2-oxaphospholane 2-oxide; rel-(2R,5R)-2-Ethoxy-5-ethyl-2,5-dihydro-2-oxido-1,2-oxaphosphol-3-yl methyl ketone; Chiral oxaphospholane derivative; Acetyl-substituted oxaphospholane oxide.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including chiral purity (enantiomeric excess) and chemical purity verification via HPLC, GC, and NMR. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are available upon request. Our quality system supports development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is likely moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.