Description

6-Fluoro-4-(Trifluoromethyl)Quinoline-2-Carboxylic Acid (97%) is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines fluorine and trifluoromethyl substituents to impart desirable electronic and steric properties in target molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-infective research programs.
• Agrochemical Development: Used to construct advanced active ingredients for crop protection products, leveraging the stability and bioactivity conferred by the fluorine atoms.
• Material Science Research: Serves as a specialized monomer or ligand in the development of functional polymers, catalysts, and organic electronic materials.
• Chemical Synthesis Building Block: Provides a versatile quinoline core for further functionalization, enabling the creation of complex molecular libraries for screening.
• Fluorinated Compound Research: An important reagent for studying the effects of fluorine substitution on molecular properties like lipophilicity, metabolic stability, and binding affinity.

Basic Information

Product Name	6-Fluoro-4-(Trifluoromethyl)Quinoline-2-Carboxylic Acid (97%)
CAS No.	596845-42-0
Molecular Formula	C₁₁H₅F₄NO₂
Molecular Weight	259.16 g/mol
Synonyms	6-Fluoro-4-(trifluoromethyl)-2-quinolinecarboxylic acid; 2-Quinolinecarboxylic acid, 6-fluoro-4-(trifluoromethyl)-; 6-Fluoro-4-trifluoromethylquinoline-2-carboxylic acid; 596845-42-0; F4-Quinoline-2-COOH derivative; 6-F-4-TFM-Q-2-COOH; Fluorinated quinoline carboxylic acid; 4-(Trifluoromethyl)-6-fluoroquinoline-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 6-Fluoro-4-(Trifluoromethyl)Quinoline-2-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot undergoes comprehensive analytical testing, including HPLC for purity verification and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, purity (≥97%), and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.