Description

2-Bromo-6-Fluoro-4-(Trifluoromethyl)Quinoline is a high-value, multi-functionalized quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique halogenated and trifluoromethylated structure makes it an indispensable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine and bromine substituents can enhance biological activity and environmental stability.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to the reactive bromine atom.
• Fluorine Chemistry: The trifluoromethyl group makes it a valuable scaffold for introducing fluorine into target molecules to modulate lipophilicity, metabolic stability, and binding affinity.

Basic Information

Product Name	2-Bromo-6-Fluoro-4-(Trifluoromethyl)Quinoline
CAS No.	596845-30-6
Molecular Formula	C₁₀H₄BrF₄N
Molecular Weight	294.05 g/mol
Synonyms	2-Bromo-6-fluoro-4-(trifluoromethyl)quinoline; 4-(Trifluoromethyl)-2-bromo-6-fluoroquinoline; Quinoline, 2-bromo-6-fluoro-4-(trifluoromethyl)-; 596845-30-6; 2-Bromo-6-fluoro-4-trifluoromethylquinoline; 6-Fluoro-2-bromo-4-(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Fluoro-4-(Trifluoromethyl)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.