Description

(R)-2,4,6-Triisopropylbenzenesulfinamide is a high-purity chiral sulfinamide compound, serving as a versatile and critical building block in asymmetric synthesis. Its primary value lies in its role as a chiral auxiliary or ligand, enabling the stereoselective formation of carbon-heteroatom and carbon-carbon bonds. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced intermediates where precise stereochemical control is paramount.

Application

• As a chiral auxiliary in the asymmetric synthesis of sulfoxides and other sulfur-containing stereogenic centers.
• Utilized as a ligand or catalyst precursor in transition metal-catalyzed asymmetric reactions.
• Key intermediate in the research and development of novel pharmaceutical compounds, especially those targeting central nervous system (CNS) disorders.
• Building block for the preparation of specialty chemicals and advanced materials requiring specific chiral configurations.
• Used in methodological development within academic and industrial organic chemistry laboratories.
• Applicable in the synthesis of agrochemicals and other bioactive molecules where enantiopurity is critical for efficacy.

Basic Information

Product Name	(R)-2,4,6-Triisopropylbenzenesulfinamide
CAS No.	592507-77-2
Molecular Formula	C15H25NOS
Molecular Weight	267.43 g/mol
Synonyms	(R)-2,4,6-Triisopropylbenzenesulfinamide; (R)-2,4,6-Triisopropylbenzenesulfonamide?; (R)-Tris(1-methylethyl)benzenesulfinamide; (R)-TIPBS; (R)-Triisopropylbenzenesulfinamide; (R)-2,4,6-Triisopropylphenylsulfinamide; Benzenesulfinamide, 2,4,6-tris(1-methylethyl)-, (R)-
EINECS	Contact for details

Quality Control

Our (R)-2,4,6-Triisopropylbenzenesulfinamide is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity, which is critical for sensitive asymmetric synthesis. Each batch is analyzed using advanced chromatographic and spectroscopic techniques, including HPLC and NMR, to verify identity, purity, and enantiomeric excess (ee). A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee batch-to-batch consistency and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere such as nitrogen or argon to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.