Description

4-{4-[(3,4-Dichlorophenyl)Sulfonyl]Piperazin-1-Yl}-2-Methylquinoline is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology applications. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers seeking reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates targeting specific biological pathways.
• Chemical Biology Research: Used as a core scaffold or probe in medicinal chemistry for structure-activity relationship (SAR) studies.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of investigational new drugs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Utilized in university and institutional labs for exploratory research in organic synthesis and pharmacology.

Basic Information

Product Name	4-{4-[(3,4-Dichlorophenyl)Sulfonyl]Piperazin-1-Yl}-2-Methylquinoline
CAS No.	591736-57-1
Molecular Formula	C20H19Cl2N3O2S
Molecular Weight	436.36 g/mol
Synonyms	4-[4-(3,4-Dichlorophenyl)sulfonylpiperazin-1-yl]-2-methylquinoline; 2-Methyl-4-[4-[(3,4-dichlorophenyl)sulfonyl]-1-piperazinyl]quinoline; 4-(4-(3,4-Dichlorophenylsulfonyl)piperazin-1-yl)-2-methylquinoline; 591736-57-1; UNII-9G6F2B8Y9F; 2-Methyl-4-(4-((3,4-dichlorophenyl)sulfonyl)piperazin-1-yl)quinoline; 4-(4-(3,4-Dichlorobenzene-1-sulfonyl)piperazin-1-yl)-2-methylquinoline
EINECS	Contact for details

Quality Control

Our 4-{4-[(3,4-Dichlorophenyl)Sulfonyl]Piperazin-1-Yl}-2-Methylquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive); therefore, containers must be kept sealed under inert atmosphere when not in use to prevent degradation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.