Description

4-Bromo-1-Methyl-1H-Indole is a halogenated indole derivative that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring a bromine atom at the 4-position, makes it an essential intermediate for constructing complex heterocyclic compounds and pharmaceuticals. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the development of new generation pesticides and herbicides with improved efficacy.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic semiconductors and advanced polymers.
• Chemical Research & Development: A fundamental reagent for exploring new palladium-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.
• Ligand and Catalyst Development: Employed in the design of novel nitrogen-containing ligands for transition metal catalysis.
• Fluorescent Dye and Sensor Synthesis: Acts as a core structure for developing indole-based fluorescent probes and imaging agents.

Basic Information

Product Name	4-Bromo-1-Methyl-1H-Indole
CAS No.	590417-55-3
Molecular Formula	C9H8BrN
Molecular Weight	210.07 g/mol
Synonyms	1-Methyl-4-bromoindole; 4-Bromo-1-methylindole; 4-Bromo-1-methyl-1H-indole; 1H-Indole, 4-bromo-1-methyl-; 4-Brom-1-methyl-1H-indol (German); 4-ブロモ-1-メチル-1H-インドール (Japanese); 4-溴-1-甲基-1H-吲哚 (Chinese)
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Methyl-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and internal quality standards. Our commitment to traceability and batch-to-batch consistency supports critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.