Description

2-Bromo-4-Trifluoromethyl-3-Quinolinecarboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in the strategic combination of a bromine substituent and a trifluoromethyl group on the quinoline scaffold, enabling precise molecular modifications and introducing desirable physicochemical properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for targets in oncology, antiviral, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used to construct novel quinoline-based molecules with potential herbicidal, fungicidal, or insecticidal activity.
• Material Science: Acts as a building block for creating advanced organic materials, such as ligands for catalysts or components for organic electronic devices.
• Chemical Biology: Employed in the development of molecular probes and tool compounds for studying biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services to clients in R&D.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical reactions involving halogenated and fluorinated heterocycles.

Basic Information

Product Name	2-Bromo-4-Trifluoromethyl-3-Quinolinecarboxylic Acid
CAS No.	590372-20-6
Molecular Formula	C11H5BrF3NO2
Molecular Weight	320.06 g/mol
Synonyms	3-Quinolinecarboxylic acid, 2-bromo-4-(trifluoromethyl)-; 2-Bromo-4-(trifluoromethyl)quinoline-3-carboxylic acid; 2-Bromo-4-trifluoromethylquinoline-3-carboxylic acid; BTFQCA; 590372-20-6; 2-Bromo-4-trifluoromethyl-3-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Trifluoromethyl-3-Quinolinecarboxylic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles. Our standard material meets a typical purity of ≥97% (HPLC), with specifications tailored to support critical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.