Description

2-Bromo-8-Iodo-4-(Trifluoromethyl)Quinoline is a high-value, multi-halogenated quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, iodine, and trifluoromethyl substituents, makes it an exceptionally versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the development of novel catalysts.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core and halogen substituents.
• Material Science & OLED Development: Serves as a building block for electron-transport materials and emissive layers in organic light-emitting diodes (OLEDs) due to its electron-deficient quinoline structure.
• Catalyst & Ligand Synthesis: Employed in the preparation of specialized nitrogen-based ligands for transition metal catalysis in cross-coupling reactions.
• Chemical Biology Probes: Utilized as a scaffold for developing fluorescent probes or photoaffinity labels for studying biological targets and mechanisms.
• Academic & Contract Research: Essential reagent for methodological development and discovery chemistry in university and CRO (Contract Research Organization) laboratories.

Basic Information

Item	Details
Product Name	2-Bromo-8-Iodo-4-(Trifluoromethyl)Quinoline
CAS No.	590372-08-0
Molecular Formula	C10H4BrF3IN
Molecular Weight	401.95 g/mol
Synonyms	2-Bromo-8-iodo-4-(trifluoromethyl)quinoline; 4-(Trifluoromethyl)-2-bromo-8-iodoquinoline; Quinoline, 2-bromo-8-iodo-4-(trifluoromethyl)-; 590372-08-0; 2-Bromo-8-iodo-4-trifluoromethylquinoline; 8-Iodo-2-bromo-4-(trifluoromethyl)quinoline
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-8-Iodo-4-(Trifluoromethyl)Quinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.