Description

Ethyl 6-Bromoh-Pyrrolo[1,2-A]Pyrazine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a brominated pyrrolopyrazine core structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce the bromine atom for further functionalization via cross-coupling reactions.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex heterocyclic frameworks common in agrochemicals and materials science.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of proprietary compounds for clinical trials.

Basic Information

Product Name	Ethyl 6-Bromoh-Pyrrolo[1,2-A]Pyrazine-3-Carboxylate
CAS No.	588720-62-1
Molecular Formula	C11H9BrN2O2
Molecular Weight	281.11 g/mol
Synonyms	Ethyl 6-Bromo-1H-pyrrolo[1,2-a]pyrazine-3-carboxylate; 6-Bromo-1H-pyrrolo[1,2-a]pyrazine-3-carboxylic acid ethyl ester; Ethyl 6-bromopyrrolo[1,2-a]pyrazine-3-carboxylate; 588720-62-1; Pyrrolo[1,2-a]pyrazine-3-carboxylic acid, 6-bromo-, ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 6-Bromoh-Pyrrolo[1,2-A]Pyrazine-3-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.