Description

4-Bromo-7-Fluoro-2-(Trifluoromethyl)Quinoline-8-Carboxylic Acid is a high-value, multi-functionalized quinoline derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and trifluoromethylated structure makes it an indispensable intermediate for creating novel compounds with tailored properties. This product is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used to construct advanced active ingredients for crop protection products, leveraging the fluorine and bromine atoms for enhanced bioactivity and environmental stability.
• Material Science: Serves as a building block for creating specialty polymers, liquid crystals, or organic electronic materials due to its rigid quinoline core and functional groups.
• Chemical Synthesis: Acts as a versatile scaffold for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) or nucleophilic substitutions, facilitated by the reactive bromine atom.
• Fluorine Chemistry: The trifluoromethyl group makes it a valuable compound for studying structure-activity relationships (SAR) and for introducing lipophilicity and metabolic stability into target molecules.

Basic Information

Product Name	4-Bromo-7-Fluoro-2-(Trifluoromethyl)Quinoline-8-Carboxylic Acid
CAS No.	587886-25-7
Molecular Formula	C11H4BrF4NO2
Molecular Weight	338.06 g/mol
Synonyms	8-Quinolinecarboxylic acid, 4-bromo-7-fluoro-2-(trifluoromethyl)-; 4-Bromo-7-fluoro-2-trifluoromethylquinoline-8-carboxylic acid; 587886-25-7; 4-Bromo-7-fluoro-2-(trifluoromethyl)-8-quinolinecarboxylic acid; 2-(Trifluoromethyl)-4-bromo-7-fluoroquinoline-8-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-7-Fluoro-2-(Trifluoromethyl)Quinoline-8-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.