Description

4-Bromo-2-(Trifluoromethyl)Quinoline-3-Carboxylic Acid is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique molecular architecture, combining a brominated quinoline core with a trifluoromethyl group and a carboxylic acid handle, enabling precise structural modifications. It is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides, leveraging the biological activity of the quinoline scaffold.
• Material Science: Serves as a building block for advanced organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient properties.
• Chemical Biology: Employed as a probe or linker in bioconjugation and the development of chemical tools for biological study.
• Catalyst & Ligand Development: The carboxylic acid and halogen groups allow for functionalization into novel chelating ligands for metal catalysis.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocycles.

Basic Information

Item	Details
Product Name	4-Bromo-2-(Trifluoromethyl)Quinoline-3-Carboxylic Acid
CAS No.	587886-11-1
Molecular Formula	C11H5BrF3NO2
Molecular Weight	320.06 g/mol
Synonyms	4-Bromo-2-(trifluoromethyl)-3-quinolinecarboxylic acid; 3-Quinolinecarboxylic acid, 4-bromo-2-(trifluoromethyl)-; 4-Bromo-2-trifluoromethylquinoline-3-carboxylic acid; 587886-11-1; 4-Bromo-2-(trifluoromethyl)quinoline-3-carboxylate; 4-Bromo-2-(trifluoromethyl)-quinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Trifluoromethyl)Quinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.