Description

6-Fluoro-2-Trifluoromethylquinoline is a high-value, multi-fluorinated heterocyclic building block essential for advanced organic synthesis. Its unique structure, featuring both fluorine and a trifluoromethyl group on the quinoline scaffold, makes it a critical intermediate for modulating the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides where the fluorine motifs improve efficacy and environmental profile.
• Material Science: Serves as a precursor for functionalized ligands in catalysis and for creating specialty polymers with unique electronic properties.
• Fluorinated Liquid Crystal Development: A building block for synthesizing novel fluorinated liquid crystal molecules used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the research of electron-transport and emissive layer materials.
• Academic & Contract Research: A valuable reagent for methodological studies in fluorination chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	6-Fluoro-2-Trifluoromethylquinoline
CAS No.	587885-96-9
Molecular Formula	C₁₀H₅F₄N
Molecular Weight	215.15 g/mol
Synonyms	2-(Trifluoromethyl)-6-fluoroquinoline; 6-Fluoro-2-(trifluoromethyl)quinoline; Quinoline, 6-fluoro-2-(trifluoromethyl)-; 6-Fluoro-2-trifluoromethyl-quinoline; 587885-96-9; 6-Fluoro-2-trifluoromethylquinoline; 2-Trifluoromethyl-6-fluoroquinoline
EINECS	Contact for details

Quality Control

Every batch of 6-Fluoro-2-Trifluoromethylquinoline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.