Description

Cyclohexaneethanol, 5-(1,1-Dimethylethyl)-2-Hydroxy-, (1R,2S,5S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its rigid cyclohexaneethanol backbone and specific hydroxyl and tert-butyl substitution, which makes it a versatile building block for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug discovery.
• Agrochemical Research: Used in the development of advanced, stereoselective pesticides and herbicides where specific spatial orientation is critical for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency and selectivity of chemical transformations.
• Flavor and Fragrance Chemistry: Potential use in the synthesis of high-value, stereochemically pure aroma chemicals and odorants.
• Material Science Research: Employed as a monomer or building block for novel polymers with specific structural and optical properties.
• Academic and R&D Laboratories: A valuable reference standard and starting material for methodological studies in stereoselective synthesis and total synthesis projects.

Basic Information

Item	Detail
Product Name	Cyclohexaneethanol, 5-(1,1-Dimethylethyl)-2-Hydroxy-, (1R,2S,5S)-Rel- (9Ci)
CAS No.	586977-44-8
Molecular Formula	C12H24O2
Molecular Weight	200.32 g/mol
Synonyms	rel-(1R,2S,5S)-5-tert-Butyl-2-hydroxycyclohexaneethanol; (1R,2S,5S)-rel-5-(tert-Butyl)-2-hydroxycyclohexaneethanol; 5-tert-Butyl-2-hydroxycyclohexaneethanol (rel-(1R,2S,5S)-isomer); 2-(5-tert-Butyl-2-hydroxycyclohexyl)ethanol; Chiral Cyclohexaneethanol Derivative; Bicyclic Alcohol Intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our Cyclohexaneethanol, 5-(1,1-Dimethylethyl)-2-Hydroxy-, (1R,2S,5S)-Rel- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.