Description

4,7-Methano-1H-Inden-1-Ol, 2,3,3A,4,7,7A-Hexahydro-, (1R,3As,4R,7S,7Ar)- (9Ci) is a high-purity, stereochemically defined bicyclic alcohol of significant interest in advanced organic synthesis. Its unique and rigid molecular framework makes it a valuable chiral building block and intermediate for the development of complex molecules. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for applications requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with complex polycyclic structures.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or starting material in catalytic asymmetric reactions to induce stereoselectivity.
• Ligand and Catalyst Development: Acts as a foundational structure for designing novel chiral ligands and organocatalysts.
• Fragrance and Flavor Chemistry: Its bicyclic scaffold can be modified to create novel odorants and flavoring agents with unique organoleptic properties.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical characteristics derived from its rigid geometry.
• Academic and Industrial R&D: Employed in methodological studies and discovery chemistry for exploring new synthetic pathways.

Basic Information

Product Name	4,7-Methano-1H-Inden-1-Ol, 2,3,3A,4,7,7A-Hexahydro-, (1R,3As,4R,7S,7Ar)- (9Ci)
CAS No.	585544-39-4
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(1R,3aS,4R,7S,7aR)-2,3,3a,4,7,7a-Hexahydro-4,7-methano-1H-inden-1-ol; Hexahydro-4,7-methano-1H-inden-1-ol (stereoisomer); Bicyclo[2.2.1]hept-5-ene-2-methanol derivative; endo-2-Hydroxymethyl-5-norbornene; Chiral norbornene alcohol intermediate; (1R,4R,7S)-1-Hydroxy-2,3,3a,4,7,7a-hexahydro-4,7-methano-1H-indene
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high chemical purity, critical for sensitive synthetic applications. Quality is verified through comprehensive analytical techniques including HPLC, GC, and chiral analysis to confirm identity, purity, and enantiomeric excess. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.