Description

2-Chloro-4-(Trifluoromethyl)Benzylamine is a versatile halogenated benzylamine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoromethyl substituents, makes it a valuable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and electronic materials requiring specific halogenated aromatic components.
• Custom Synthesis and Contract Manufacturing: A high-value intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethyl)Benzylamine
CAS No.	581813-20-9
Molecular Formula	C8H7ClF3N
Molecular Weight	209.60 g/mol
Synonyms	1-(2-Chloro-4-(trifluoromethyl)phenyl)methanamine; (2-Chloro-4-(trifluoromethyl)phenyl)methanamine; 2-Chloro-α,α,α-trifluoro-p-toluidine; 2-Chloro-4-trifluoromethylbenzylamine; α-(Trifluoromethyl)-2-chloro-4-aminotoluene; Benzenemethanamine, 2-chloro-4-(trifluoromethyl)-; 2-Chloro-4-(trifluoromethyl)benzenemethanamine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Trifluoromethyl)Benzylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.