Description

Benzo[B]Thiophene-2-Carboxylic Acid, 3-Chloro-6-Methoxy-, 2-(1-Naphthalenylacetyl)Hydrazide (9Ci) is a sophisticated heterocyclic organic compound featuring a benzo[b]thiophene core functionalized with chloromethoxy and naphthalene-acetyl hydrazide groups. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries. The compound's specific structure is designed for the synthesis of novel active ingredients targeting a range of therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Medicinal Chemistry Research: Used as a specialized scaffold for structure-activity relationship (SAR) studies and high-throughput screening libraries to discover new bioactive molecules.
• Agrochemical Development: Acts as a key building block for creating new-generation herbicides, fungicides, or insecticides with unique modes of action.
• Chemical Biology Probe: Employed in biochemical assays to study enzyme inhibition or receptor-ligand interactions due to its distinct heterocyclic structure.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct more complex polycyclic or fused-ring systems for material science applications.

Basic Information

Item	Details
Product Name	Benzo[B]Thiophene-2-Carboxylic Acid, 3-Chloro-6-Methoxy-, 2-(1-Naphthalenylacetyl)Hydrazide (9Ci)
CAS No.	581782-11-8
Molecular Formula	C22H17ClN2O3S
Molecular Weight	424.90 g/mol
Synonyms	3-Chloro-6-methoxybenzo[b]thiophene-2-carboxylic acid 2-(1-naphthylacetyl)hydrazide; 2-(1-Naphthalenylacetyl)hydrazide of 3-Chloro-6-methoxybenzo[b]thiophene-2-carboxylic acid; 3-Chloro-6-methoxy-1-benzothiophene-2-carboxylic acid (1-naphthylacetyl)hydrazide; (3-Chloro-6-methoxybenzo[b]thiophen-2-yl)-N'-(naphthalen-1-ylacetyl)formohydrazide; 581782-11-8; Benzo[B]Thiophene-2-Carboxylic Acid, 3-Chloro-6-Methoxy-, 2-(1-Naphthalenylacetyl)Hydrazide; Hydrazide derivative of 3-chloro-6-methoxybenzo[b]thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and MS to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting critical quality attributes. For customers with specific purity requirements, such as those for GMP-grade pharmaceutical development, custom synthesis and enhanced QC protocols are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.