Description

Carbamic Acid, [3-[(2-Chlorophenyl)Methyl]-3,4-Dihydro-4-Oxo-2-Propyl-6-Quinazolinyl]-, 1,1-Dimethylethyl Ester (9Ci) is a high-purity, advanced pharmaceutical intermediate with the CAS number 579523-64-1. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring quinazolinone-based scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities for drug discovery and process optimization.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of proprietary drug candidates, especially those targeting kinase inhibition.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the manufacturing of complex organic molecules.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API production.
• Chemical Biology Probes: Utilized in the development of biochemical tools for studying enzyme function and cellular pathways.

Basic Information

Product Name	Carbamic Acid, [3-[(2-Chlorophenyl)Methyl]-3,4-Dihydro-4-Oxo-2-Propyl-6-Quinazolinyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	579523-64-1
Molecular Formula	C24H26ClN3O3
Molecular Weight	439.94 g/mol
Synonyms	tert-Butyl N-[3-[(2-chlorophenyl)methyl]-4-oxo-2-propyl-3,4-dihydroquinazolin-6-yl]carbamate; 6-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-[(2-chlorophenyl)methyl]-2-propyl-3H-quinazolin-4-one; Carbamic acid, N-[3-[(2-chlorophenyl)methyl]-4-oxo-2-propyl-3,4-dihydro-6-quinazolinyl]-, 1,1-dimethylethyl ester; 579523-64-1; Quinazolinone carbamate derivative; 2-Propyl-3-(2-chlorobenzyl)-6-((tert-butoxycarbonyl)amino)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [3-[(2-Chlorophenyl)Methyl]-3,4-Dihydro-4-Oxo-2-Propyl-6-Quinazolinyl]-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.