Description

9-Oxatricyclo[4.2.1.12,5]Decan-10-One,3-Ethyl-2,5-Dimethyl-,(1R,2R,3R,5S,6S)-Rel-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is valued for its complex, rigid oxatricyclic scaffold, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates targeting the central nervous system (CNS) or other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry Development: Serves as a starting material or intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Asymmetric Synthesis: Utilized in the construction of complex molecules requiring specific stereochemistry due to its defined (1R,2R,3R,5S,6S) configuration.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university laboratories for studies in organic synthesis methodology and novel heterocyclic chemistry.

Basic Information

Product Name	9-Oxatricyclo[4.2.1.12,5]Decan-10-One,3-Ethyl-2,5-Dimethyl-,(1R,2R,3R,5S,6S)-Rel-(9Ci)
CAS No.	578714-71-3
Molecular Formula	C13H20O2
Molecular Weight	208.30 g/mol
Synonyms	(1R,2R,3R,5S,6S)-3-Ethyl-2,5-dimethyl-9-oxatricyclo[4.2.1.12,5]decan-10-one; rel-(1R,2R,3R,5S,6S)-3-Ethyl-2,5-dimethyl-9-oxatricyclo[4.2.1.12,5]decan-10-one; 3-Ethyl-2,5-dimethyl-9-oxatricyclo[4.2.1.1²,⁵]decan-10-one (rel-(1R,2R,3R,5S,6S)-form); Oxatricyclic ketone intermediate; 578714-71-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We offer material suitable for research and development under a quality-managed system. For advanced projects, we can discuss supply under higher-tier quality agreements. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are available upon request for every batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.