Description

3-Quinolinecarbonitrile,2-Amino-5,6,7,8-Tetrahydro-4-(4-Pyridinyl)-(9Ci) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and oncological targets.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting kinase inhibition.
• Drug Discovery Research: Serves as a versatile scaffold in medicinal chemistry for constructing libraries of novel compounds for biological screening.
• Chemical Reference Standard: Used as a high-purity standard in analytical method development and quality control for API manufacturing.
• Process Chemistry Development: Employed in optimizing scalable synthetic routes for potential new chemical entities (NCEs).
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	3-Quinolinecarbonitrile,2-Amino-5,6,7,8-Tetrahydro-4-(4-Pyridinyl)-(9Ci)
CAS No.	577985-54-7
Molecular Formula	C₁₅H₁₄N₄
Molecular Weight	250.30 g/mol
Synonyms	2-Amino-4-(pyridin-4-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile; 4-(4-Pyridinyl)-2-amino-5,6,7,8-tetrahydro-3-quinolinecarbonitrile; 2-Amino-4-(4-pyridyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile; 577985-54-7; 2-Amino-4-(4-pyridinyl)-5,6,7,8-tetrahydro-3-quinolinecarbonitrile; Tetrahydroquinoline derivative, 2-amino-4-(4-pyridinyl)-3-cyano-; 3-Cyano-2-amino-4-(4-pyridyl)-5,6,7,8-tetrahydroquinoline
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We provide comprehensive analytical data to support its use in regulated environments, with specifications typically covering identity, purity, and related substances. Certificates of Analysis (COA) detailing results from HPLC, NMR, and mass spectrometry are available for each lot to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.