Description

6-Ethoxy-7-Methoxyquinazoline-4-One is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinone class of heterocyclic compounds. Its precise molecular structure makes it a critical building block for the synthesis of targeted therapeutic agents, particularly kinase inhibitors. This compound is essential for research and development laboratories, as well as production facilities, in the pharmaceutical and fine chemical industries seeking to develop novel drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potent kinase inhibitors and other biologically active quinazoline derivatives.
• Oncology Drug Research: Serves as a core scaffold for developing tyrosine kinase inhibitors (TKIs) targeting various cancer pathways.
• Chemical Synthesis Building Block: Used in organic synthesis to introduce the functionalized quinazolinone moiety into more complex molecular architectures.
• Biochemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and enzyme inhibition mechanisms.
• Fine Chemical Production: Integral to the manufacture of high-value specialty chemicals for the life sciences sector.

Basic Information

Product Name	6-Ethoxy-7-Methoxyquinazoline-4-One
CAS No.	577728-29-1
Molecular Formula	C₁₂H₁₂N₂O₃
Molecular Weight	232.24 g/mol
Synonyms	4(3H)-Quinazolinone, 6-ethoxy-7-methoxy-; 6-Ethoxy-7-methoxy-4(3H)-quinazolinone; 7-Methoxy-6-ethoxyquinazolin-4(3H)-one; 6-Ethoxy-7-methoxy-3,4-dihydroquinazolin-4-one; Quinazolin-4(3H)-one, 6-ethoxy-7-methoxy-
EINECS	Contact for details

Quality Control

Every batch of 6-Ethoxy-7-Methoxyquinazoline-4-One is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications tailored for pharmaceutical intermediate applications. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.