Description

4-Bromo-6,8-Difluoroquinoline is a high-purity, multi-functional halogenated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine and fluorine substituents at strategic positions, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for fluorinated quinolone-based antibiotics and other therapeutic agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the difluoroquinoline scaffold contributes to bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and fluorescent tags for diagnostic and research applications.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel nitrogen-containing ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A versatile substrate for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Bromo-6,8-Difluoroquinoline
CAS No.	577692-34-3
Molecular Formula	C9H4BrF2N
Molecular Weight	244.04 g/mol
Synonyms	6,8-Difluoro-4-bromoquinoline; 4-Bromo-6,8-difluoroquinoline; Quinoline, 4-bromo-6,8-difluoro-; 4-Brom-6,8-difluorchinolin; 4-Bromo-6,8-difluorochinolin
EINECS	Contact for details

Quality Control

Every batch of 4-Bromo-6,8-Difluoroquinoline is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.