Description

(R)-(+)-1-(2-Pyrrolidinylmethyl)Piperidine is a high-purity chiral piperidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and ligand precursor for the development of pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and industrial R&D departments focused on asymmetric catalysis, medicinal chemistry, and the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalysis: Used as a precursor for synthesizing chiral ligands and organocatalysts essential for enantioselective synthesis.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the construction of complex molecular libraries for high-throughput screening.
• Fine Chemical Synthesis: Serves as a specialized building block for creating high-value, optically active compounds in agrochemical and material science research.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis at university and corporate research labs.

Basic Information

Product Name	(R)-(+)-1-(2-Pyrrolidinylmethyl)Piperidine
CAS No.	575469-26-0
Molecular Formula	C10H20N2
Molecular Weight	168.28 g/mol
Synonyms	(R)-(+)-1-[(2-Pyrrolidinyl)methyl]piperidine; (R)-1-((Pyrrolidin-2-yl)methyl)piperidine; (R)-1-(Pyrrolidin-2-ylmethyl)piperidine; (R)-(+)-1-(2-Pyrrolidinylmethyl)piperidine; (R)-Pyrrolidin-2-ylmethyl-piperidine; (R)-2-(Piperidin-1-ylmethyl)pyrrolidine; (R)-1-(Piperidin-1-ylmethyl)pyrrolidine (tautomer); (R)-N-(2-Pyrrolidinylmethyl)piperidine
EINECS	Contact for details

Quality Control

Our (R)-(+)-1-(2-Pyrrolidinylmethyl)Piperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.