Description

S-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Diphenyl-[1,1'-Binaphthalene]-2,2'-Diol is a high-value, chiral binaphthol derivative, serving as a sophisticated ligand and building block in asymmetric synthesis. Its rigid, three-dimensional structure is critical for inducing high enantioselectivity in catalytic reactions, directly impacting the efficiency and purity of advanced chemical manufacturing. This compound is essential for research and production in the pharmaceutical and fine chemical sectors, where precise stereochemical control is paramount for developing active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Asymmetric Catalysis: As a privileged chiral ligand for transition metal catalysts (e.g., Rh, Ru, Pd) in hydrogenation, coupling, and cycloaddition reactions.
• Pharmaceutical Intermediate Synthesis: A key precursor in the multi-step synthesis of complex, stereochemically defined drug molecules and bioactive compounds.
• Chiral Auxiliary: Used to temporarily impart chirality in organic synthesis, enabling the stereoselective formation of new bonds.
• Material Science Research: A building block for developing chiral polymers, liquid crystals, and molecular recognition systems.
• Academic & Industrial R&D: A valuable tool for method development and discovery chemistry in laboratories worldwide.

Basic Information

Product Name	S-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Diphenyl-[1,1'-Binaphthalene]-2,2'-Diol
CAS No.	575451-08-0
Molecular Formula	C32H30O2
Molecular Weight	446.58 g/mol
Synonyms	(S)-H8-BINOL; (S)-Octahydro-1,1'-bi-2-naphthol; (S)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-bi-2-naphthol; (S)-H8-BINOL; (S)-1,1'-Bi-2-naphthol, 5,5',6,6',7,7',8,8'-octahydro-; S-Octahydrobinaphthol; S-H8BINOL; (S)-3,3'-Diphenyl-H8-BINOL
EINECS	Contact for details

Quality Control

Our S-5,5',6,6',7,7',8,8'-Octahydro-3,3'-Diphenyl-[1,1'-Binaphthalene]-2,2'-Diol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and chiral integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.